Document Detail


Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity?
MedLine Citation:
PMID:  20303035     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Because most extremely preterm infants with birth weight less than 1000 g need red blood cell transfusions, many attempts have been made to collect, process, and store placental blood (ie, umbilical cord blood) for autologous transfusions. Although it is feasible to do this, multiple problems in doing so including insufficient volumes collected, clotting, hemolysis, bacterial contamination, failure to significantly supplant need for allogeneic transfusions, and high costs have led many to question whether, on balance, autologous/placental red blood cell transfusion offers clinically significant benefits.
Authors:
Ronald G Strauss; John A Widness
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Transfusion medicine reviews     Volume:  24     ISSN:  1532-9496     ISO Abbreviation:  Transfus Med Rev     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-06-01     Revised Date:  2012-01-24    
Medline Journal Info:
Nlm Unique ID:  8709027     Medline TA:  Transfus Med Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Copyright Information:
(c) 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA. ronald-strauss@uiowa.edu
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MeSH Terms
Descriptor/Qualifier:
Anemia, Neonatal / therapy*
Blood Transfusion, Autologous / utilization*
Erythrocyte Transfusion / utilization*
Female
Fetal Blood / transplantation*
Health Services Needs and Demand
Humans
Infant, Newborn
Placental Circulation / physiology
Pregnancy
Grant Support
ID/Acronym/Agency:
P01 HL046925/HL/NHLBI NIH HHS; P01 HL046925-14/HL/NHLBI NIH HHS
Comments/Corrections
Comment In:
Transfus Med Rev. 2012 Jan;26(1):90-1; author reply 91-2   [PMID:  21831582 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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