Document Detail

Is There a Necessity for Individual Blood Water Corrections when Conductivity-Based Access Blood Flow Measurements Are Made?
MedLine Citation:
PMID:  21811064     Owner:  NLM     Status:  Publisher    
Background/Aims:Access blood water flow rate (Qaw) can be measured during hemodialysis using an online effective ionic dialysance (EID) methodology. Fresenius employ this methodology in their 2008K dialysis machine. The machine computer converts Qaw to an access blood flow rate (Fresenius Qa) using a generic blood water constant (BWC). We wished to validate this BWC. Methods: 18 patients had Fresenius Qa measurements using the EID and these were compared with a 'gold standard' ultrasound dilution methodology (Transonic Qa). Qa values were also obtained by removing the BWC from Fresenius Qa values to obtain the Qaw and recorrecting it with individualized patient factors using hematocrit and total protein values (HctTp Qa). The measurements were repeated after 1 h. Results:There were no significant differences between Fresenius and Transonic, nor between HctTp and Transonic Qa values (p > 0.17). There were strong correlations between both sets of values (r > 0.856; p < 0.001). There was a significant correlation between the pairs of Transonic Qa values (r = 0.823; p < 0.007), but not for Fresenius Qa pairs (r = 0.573; p > 0.07). It was surmised that the BWC was not valid post-dialysis. Conclusion:The generic BWC is comparable to individualized blood water correction factors when Qa measures are made early in dialysis and prior to ultrafiltration treatment.
Shih-Han S Huang; Paul A Heidenheim; Kerri Gallo; Saumya Jayakumar; Robert M Lindsay
Related Documents :
2504134 - Eicosanoid release as laboratory indicator of biocompatibility.
1519174 - Correction of steal syndrome secondary to hemodialysis access fistulas: a simplified qu...
24570764 - Inspiratory flows and volumes in subjects with non-cf bronchiectasis using a new dry po...
15043624 - The allient dialysis system.
6637544 - Arterial pressure-blood flow relations during limb elevation in man.
712604 - Evaluation of an oral prolonged-release antibiotic formulation.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-29
Journal Detail:
Title:  Blood purification     Volume:  32     ISSN:  1421-9735     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-8-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402040     Medline TA:  Blood Purif     Country:  -    
Other Details:
Languages:  ENG     Pagination:  174-180     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Division of Nephrology, Department of Medicine, University of Western Ontario, and London Health Sciences Centre, London, Ont., Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Resting Metabolic Rate in Elite Rowers and Canoeists: Difference between Indirect Calorimetry and Pr...
Next Document:  Does Antifungal Prophylaxis with Daily Oral Fluconazole Reduce the Risk of Fungal Peritonitis in Per...