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Is There Any Correlation between Insulin Resistance and Nitrate Plasma Concentration in White Coat Hypertensive Patients?
MedLine Citation:
PMID:  19936118     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We evaluated a relationship between nitric oxide plasma correlation and insulin resistance in white coat hypertensive patients. Patients were screened for white coat hypertension using an ambulatory blood pressure monitoring. The homeostasis model assessment insulin resistance index (HOMA-IR) was used to assess insulin resistance, and plasma nitrate concentrations were determined by chemiluminescence. The HOMA-IR was significantly higher in hypertensive (3.84 +/- 0.62) when compared to white coat (2.11 +/- 0.36) and normotensive (1.40 +/- 0.21). We found no correlation between HOMA-IR and plasma nitrate levels in all three groups. We suggest that the more important issue for these patients is to focus on the metabolic abnormalities where lifestyle interventions such as weight control and exercise have proven effective.
Authors:
Leila Maria Marchi-Alves; Evelin Capellari Carnio
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Publication Detail:
Type:  Journal Article     Date:  2009-08-24
Journal Detail:
Title:  Cardiology research and practice     Volume:  2009     ISSN:  2090-0597     ISO Abbreviation:  Cardiol Res Pract     Publication Date:  2009  
Date Detail:
Created Date:  2009-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101516542     Medline TA:  Cardiol Res Pract     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  376735     Citation Subset:  -    
Affiliation:
Departamento de Enfermagem Geral e Especializada, Escola de Enfermagem de Ribeirão Preto/Universidade de São Paulo, Avenida Bandeirantes, 3900, 14040-902-Ribeirão Preto, SP, Brazil.
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