Document Detail


Therapy of difficult cases of canine pyoderma with marbofloxacin: a report of 39 dogs.
MedLine Citation:
PMID:  10404486     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty-nine dogs with severe and/or recurrent lesions of pyoderma were treated with marbofloxacin at an average dosage of 2.12 mg/kg bodyweight, once daily, for time periods varing from 10 to 213 days. Forty-seven strains of bacteria, isolated from 34 cultures, were tested for sensitivity to various antibiotics. At day 0, no resistance to marbofloxacin was found, but one refractory case, a strain of Staphylococcus intermedius resistant to marbofloxacin, was cultured at day 28. Thirty-three dogs (84.6 per cent) showed an excellent response (cure), one (2.6 per cent) a clear improvement and one (2.6 per cent) a smaller improvement, while the remaining four dogs showed no response after 11 to 60 days. Fifteen dogs (45.5 per cent) relapsed over the follow-up period of three to 191 days, but none of the dogs in the study exhibited any adverse effects.
Authors:
D N Carlotti; E Guaguere; D Pin; P Jasmin; E Thomas; V Guiral
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of small animal practice     Volume:  40     ISSN:  0022-4510     ISO Abbreviation:  J Small Anim Pract     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-08-31     Completed Date:  1999-08-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0165053     Medline TA:  J Small Anim Pract     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  265-70     Citation Subset:  IM    
Affiliation:
Cabinet de Dermatologie Vétérinaire, Bordeaux-Mérignac, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Infective Agents / administration & dosage*
Body Weight
Cellulitis / drug therapy,  microbiology,  veterinary
Dog Diseases / drug therapy*
Dogs
Enzyme Inhibitors / administration & dosage*
Erythema / drug therapy,  microbiology,  veterinary
Female
Fluoroquinolones*
Folliculitis / drug therapy,  microbiology,  veterinary
Follow-Up Studies
Male
Microbial Sensitivity Tests
Pruritus / drug therapy,  microbiology,  veterinary
Pyoderma / drug therapy*,  microbiology,  veterinary*
Quinolones / administration & dosage*
Recurrence
Skin Ulcer / drug therapy,  microbiology,  veterinary
Staphylococcal Infections / drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Enzyme Inhibitors; 0/Fluoroquinolones; 0/Quinolones; 115550-35-1/marbofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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