| Therapy for diastolic heart failure. | |
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MedLine Citation:
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PMID: 16115517 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is little objective to guide the therapy of patients with diastolic heart failure. Because of the similarities of pathophysiology abnormalities in diastolic and systolic heart failure, it is a reasonable inference to suggest that the proven therapy for systolic heart failure may also be of benefit in patients with diastolic heart failure. Treatment of underlying or exacerbating conditions in diastolic heart failure, such as hypertension, left ventricular hypertrophy, ischemia, diabetes, anemia, obesity and pulmonary disease is an important means of managing diastolic heart failure. Control of systolic blood pressure is effective in improving and preventing the development of diastolic heart failure. Treatment of diastolic heart failure is most effective when it is associated with hypertension. Production of systolic arterial pressure acutely reduces pulmonary congestion, ischemia, and chronically may lead to regression of left ventricular hypertrophy. Patients with diastolic heart failure in the absence of hypertension are very difficult to treat. |
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Authors:
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William C Little; Steffen Brucks |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Progress in cardiovascular diseases Volume: 47 ISSN: 0033-0620 ISO Abbreviation: Prog Cardiovasc Dis Publication Date: 2005 May-Jun |
Date Detail:
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Created Date: 2005-08-23 Completed Date: 2005-10-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376442 Medline TA: Prog Cardiovasc Dis Country: United States |
Other Details:
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Languages: eng Pagination: 380-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Cardiology Section, Wake Forest University School of Medicine Winston-Salem, NC, USA. wlittle@wfubmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Angiotensin-Converting Enzyme Inhibitors / therapeutic use* Blood Pressure* / drug effects, physiology Diastole Heart Failure* / drug therapy, physiopathology Humans Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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