Document Detail

Therapy of brain arteriovenous malformations: multimodality treatment from a balanced standpoint.
MedLine Citation:
PMID:  17053597     Owner:  NLM     Status:  MEDLINE    
The three therapeutic modalities for arteriovenous malformation (AVM) treatment (surgery, embolization, and radiotherapy) developed in the past years with specific tools, each tool with its own qualities. Soon after the implementation of embolization for treatment of AVMs, this technique was used in combination with microsurgery; since the development of radiosurgery, treatment algorithms combining embolization with surgery and eventual subsequent radiosurgery, embolization with radiosurgery, or surgery with subsequent radiosurgery have been reported. These different combinations have been in use under the term multimodality treatment for many years, but the algorithms regarding the combination of tools, which tool has priority, and how the risk levels of each tool are assessed shows great variability among institutions. Centers with a surgical background see embolization as a technique to increase surgical feasibility and radiosurgery as a tool to complete subtotal AVM excision. Institutions with an endovascular background embolize AVMs with the aim of maximal occlusion rates and view surgery or radiosurgery as a technique to be used if the goal of total endovascular occlusion cannot be achieved. Radiosurgeons receive patients after incomplete embolization or surgical extirpation or a combination of both.
Bernd Richling; Monika Killer; Abdul R Al-Schameri; Lutz Ritter; Rada Agic; Michael Krenn
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neurosurgery     Volume:  59     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-20     Completed Date:  2007-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S148-57; discussion S3-13     Citation Subset:  IM    
Department of Neurosurgery, Paracelsus Private Medical University, Salzburg, Austria.
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MeSH Terms
Blood Vessel Prosthesis / trends
Catheterization / trends*
Combined Modality Therapy / trends
Embolization, Therapeutic / trends*
Intracranial Arteriovenous Malformations / therapy*
Neurosurgical Procedures / trends*
Radiosurgery / trends*
Reconstructive Surgical Procedures / trends
Treatment Outcome
Vascular Surgical Procedures / trends*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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