| Therapies for scleroderma-related pulmonary arterial hypertension. | |
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MedLine Citation:
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PMID: 19885388 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Pulmonary arterial hypertension (PAH), a common complication of systemic sclerosis, carries a very severe prognosis and is one of the leading causes of death in patients who suffer from it. Indeed, response to modern medical therapy has been disappointing in scleroderma-related PAH compared with other forms of PAH from the WHO group 1 classification of diseases, despite similar histological changes involving the pulmonary vasculature. This review discusses specific features of scleroderma-related PAH, currently available and US FDA-approved therapy for this syndrome, as well as potential future therapeutic developments based on newly acquired knowledge of this disorder. |
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Authors:
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Paul M Hassoun |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Expert review of respiratory medicine Volume: 3 ISSN: 1747-6348 ISO Abbreviation: Expert Rev Respir Med Publication Date: 2009 |
Date Detail:
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Created Date: 2009-11-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101278196 Medline TA: Expert Rev Respir Med Country: - |
Other Details:
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Languages: ENG Pagination: 187-196 Citation Subset: - |
Affiliation:
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Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD 21224, USA, Tel.: +1 410 614 5158, , phassoun@jhmi.edu. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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P50 HL084946-01//NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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