Document Detail

Therapies administered to mothers at risk for preterm birth and neurodevelopmental outcome in their infants.
MedLine Citation:
PMID:  12516743     Owner:  NLM     Status:  MEDLINE    
A decrease in the rate of preterm births and the prevention of prematurity-associated neurodevelopmental morbidity are critical for the reduction of neurodevelopmental disability. Efforts to reduce the overall preterm delivery rate have been unsuccessful. Although progress has been achieved in the prevention of short-term neonatal morbidity over the past several decades, the majority of the improvements have resulted from improved neonatal care. Whether obstetric interventions can improve neurodevelopmental outcome is unknown. The ability to adequately assess obstetric interventions is hampered by the limited number of interventional studies that included long-term outcome assessment. Thus, it is incumbent upon ongoing and future interventional studies to consider long-term outcome assessment as a critical component of the overall evaluation of efficacy of obstetric therapies.
Patrick S Ramsey; Dwight J Rouse
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  29     ISSN:  0095-5108     ISO Abbreviation:  Clin Perinatol     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2003-01-08     Completed Date:  2003-01-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  725-43     Citation Subset:  IM    
Center for Research in Women's Health, University of Alabama at Birmingham, Department of Obstetrics and Gynecology 458 Old Hillman Building, 619 19th Street South, Birmingham, AL 35249-7333, USA.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Developmental Disabilities / etiology*,  prevention & control*
Excitatory Amino Acid Antagonists / therapeutic use
Fetal Growth Retardation / complications,  therapy
Fetal Monitoring
Infant Mortality
Infant, Newborn
Intensive Care, Neonatal / methods*,  trends
Obstetric Labor, Premature / complications*,  epidemiology,  therapy*
Phenobarbital / therapeutic use
Pregnancy Outcome
Prenatal Care / methods*,  standards,  trends
Risk Factors
Treatment Outcome
Vitamin K / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents; 0/Excitatory Amino Acid Antagonists; 0/Steroids; 12001-79-5/Vitamin K; 50-06-6/Phenobarbital

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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