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Therapeutic potential of marine n-3 fatty acids in CABG patients.
MedLine Citation:
PMID:  22321570     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Dietary intake of marine n-3 polyunsaturated fatty acids (PUFA) has beneficial effects in various cardiac disorders. Few studies have, however, investigated the therapeutic potential of n-3 PUFA in patients undergoing coronary artery bypass grafting (CABG). Five heterogeneous randomized studies on n-3 PUFA for prevention of postoperative atrial fibrillation have yielded conflicting results. Increased venous graft patency rates following CABG were seen in another study in patients treated with n-3 PUFA. Finally, supplements with n-3 PUFA postoperatively have been associated with a lower risk of repeat revascularization and lower mortality in patients with poor ventricular function. Data are still few, and more studies are needed to clarify the therapeutic potential of n-3 PUFA in patients undergoing CABG.
Authors:
Jan Jesper Andreasen; Erik Berg Schmidt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-7
Journal Detail:
Title:  Current opinion in pharmacology     Volume:  -     ISSN:  1471-4973     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100966133     Medline TA:  Curr Opin Pharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Cardiothoracic Surgery, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Hobrovej, PO Box 365, 9100 Aalborg, Denmark.
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