Document Detail


Therapeutic potential of argan oil: a review.
MedLine Citation:
PMID:  21054392     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The therapeutic benefits of argan oil consumption have been claimed by natives of Morocco and explorers for more than eight centuries. However, argan oil has remained unresearched for a long time. Traditionally, argan oil has been well known for its cardioprotective properties and it is also used in the treatment of skin infections. Argan oil is principally composed of mono-unsaturated (up to 80%) and saturated (up to 20%) fatty acids. As minor components, it contains polyphenols, tocopherols, sterols, squalene, and triterpene alcohols. Together with the mono-unsaturated fatty acids, these minor components are likely to be responsible for its beneficial effects. This review aims to present an overview of the known pharmacological properties of argan oil.
KEY FINDINGS: Antiproliferative, antidiabetic, and cardiovascular-protective effects of argan oil have been particularly actively evaluated over the last 5 years in order to build on phytochemical studies that indicate the presence of large amounts of possibly pharmacologically active compounds.
SUMMARY: This review shows that a lack of clinical data constitutes a serious weakness in our knowledge about argan oil, therefore it is difficult to correlate the reported pharmacological activities to any potential clinical relevance.
Authors:
Hanae El Monfalouti; Dom Guillaume; Clément Denhez; Zoubida Charrouf
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of pharmacy and pharmacology     Volume:  62     ISSN:  2042-7158     ISO Abbreviation:  J. Pharm. Pharmacol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-08     Completed Date:  2011-05-11     Revised Date:  2011-09-13    
Medline Journal Info:
Nlm Unique ID:  0376363     Medline TA:  J Pharm Pharmacol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1669-75     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. JPP © 2010 Royal Pharmaceutical Society of Great Britain.
Affiliation:
Université de Reims Champagne Ardenne, Laboratoire de Chimie Thérapeutique, 51 Rue Cognacq Jay, 51100 Reims, France.
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / prevention & control
Dietary Supplements
Fatty Acids / chemistry,  pharmacology
Fatty Acids, Unsaturated / chemistry,  pharmacology
Flavonoids / analysis
Fruit
Humans
Morocco
Obesity / prevention & control
Phenols / analysis
Phytotherapy*
Plant Extracts / administration & dosage,  chemistry,  pharmacology*
Plant Oils / administration & dosage,  chemistry,  pharmacology*
Sapotaceae*
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Fatty Acids, Unsaturated; 0/Flavonoids; 0/Phenols; 0/Plant Extracts; 0/Plant Oils; 0/polyphenols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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