Document Detail


Therapeutic plasma exchange in amitriptyline intoxication: case report and review of the literature.
MedLine Citation:
PMID:  21872530     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe amitriptyline poisoning results in cardiac and neurological toxicity and continues to be a leading cause of significant morbidity and mortality both in children and adults. We present a case of severe amitriptyline poisoning successfully treated with plasma exchange. Due to high plasma protein binding property of amitriptyline, plasma exchange therapy should be considered in cases of severe amitriptyline intoxication as a life saving therapeutic modality.
Authors:
Ismail Sari; Ibrahim Turkcuer; Tuba Erurker; Mustafa Serinken; Murat Seyit; Ali Keskin
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2011-08-26
Journal Detail:
Title:  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis     Volume:  45     ISSN:  1473-0502     ISO Abbreviation:  Transfus. Apher. Sci.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-05     Completed Date:  2012-04-11     Revised Date:  2012-06-14    
Medline Journal Info:
Nlm Unique ID:  101095653     Medline TA:  Transfus Apher Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  183-5     Citation Subset:  T    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Pamukkale University, Faculty of Medicine, Department of Hematology, Therapeutic Apheresis Unit, Denizli, Turkey. hisari@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amitriptyline / poisoning*
Antidepressive Agents, Tricyclic / poisoning*
Child, Preschool
Female
Humans
Plasma Exchange / methods*
Plasmapheresis
Young Adult
Chemical
Reg. No./Substance:
0/Antidepressive Agents, Tricyclic; 50-48-6/Amitriptyline
Comments/Corrections
Comment In:
Transfus Apher Sci. 2012 Jun;46(3):353   [PMID:  22082656 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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