| Therapeutic options for immune-mediated thrombocytopenia. | |
| | |
MedLine Citation:
|
PMID: 22316417 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: To review the therapeutic options for immune-mediated thrombocytopenia (IMT). DATA SOURCES: Original research publications and review articles using the PubMed search engine for the phrases "immune-mediated thrombocytopenia" or "immune thrombocytopenic purpura" or "immune thormbocytopenia." VETERINARY AND HUMAN DATA SYNTHESIS: There are a number of therapeutic options for adult-onset immune thrombocytopenia in human medicine with demonstrated efficacy in clinical studies although corticosteroids and immunoglobulin therapy remain the first-line medical treatments. Thrombopoietin receptor agonist therapy and, to a lesser extent, rituximab have shown great promise in initial clinical trials and may become standard of care in human medicine for the management of IMT. Therapeutic options in veterinary medicine are less diverse and only vincristine and human intravenous immunoglobulin therapies have been evaluated in controlled clinical studies. CONCLUSIONS: There are a number of therapeutic options in the management of IMT veterinary medicine, most of which have not been investigated in clinical studies. Further research is warranted to best identify the optimal treatment strategy for IMT in veterinary patients. |
| | |
Authors:
|
Reid K Nakamura; Emily Tompkins; Domenico Bianco |
Related Documents
:
|
14269437 - Forensic medicine: an aid to criminal investigation. 18730147 - The scope and responsibility of medicine-a forum with a purpose. 20578557 - Impact on access to medicines from trips-plus: a case study of thai-us fta. 20234967 - Access to medicines and domestic compulsory licensing: learning from canada and thailand. 20166907 - The impact of the coronial communiqu? on changing patient safety: a subscriber survey. 21919847 - Quinazolinone analogs as potential therapeutic agents. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-25 |
Journal Detail:
|
Title: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) Volume: - ISSN: 1476-4431 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-2-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101152804 Medline TA: J Vet Emerg Crit Care (San Antonio) Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© Veterinary Emergency and Critical Care Society 2012. |
Affiliation:
|
From the Advanced Veterinary Care Center, Lawndale, CA 90260. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Medication abortion within a student health care clinic: a review of the first 46 consecutive cases.
Next Document: Multi-level soft lithography with micrometer alignment using all-flexible rubber stamps and moiré f...