Document Detail


Therapeutic options of caesarean scar pregnancy: case series and literature review.
MedLine Citation:
PMID:  19902518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe our experience with the treatment of 4 caesarean scar pregnancies and provide an overview of current literature. Four women diagnosed with a caesarean scar pregnancy in our hospital between 1996 and 2007 were treated with local or systemic methotrexate and had a steady decline of the serum beta-hCG level. The uterus was preserved in all women and 3 of them had an uneventful subsequent pregnancy and delivery. We suggest that transcervical needle aspiration of amniotic fluid followed by intra-amniotic injection of methotrexate should be the treatment of choice, followed by surgical treatment only if methotrexate fails.
Authors:
A J Marjolein Bij de Vaate; Hans A M Br?lmann; Johannes W van der Slikke; Maurice G A J Wouters; Roel Schats; Judith A F Huirne
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  38     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-13     Completed Date:  2010-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  75-84     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley Periodicals, Inc.
Affiliation:
Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amnion
Antimetabolites, Antineoplastic / administration & dosage,  therapeutic use
Cesarean Section / adverse effects*
Cicatrix / complications*,  ultrasonography
Endosonography
Female
Follow-Up Studies
Humans
Injections
Laparotomy / methods*
Methotrexate / administration & dosage,  therapeutic use*
Myometrium
Pregnancy
Pregnancy, Ectopic / etiology,  therapy*,  ultrasonography
Chemical
Reg. No./Substance:
0/Antimetabolites, Antineoplastic; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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