Document Detail


Therapeutic myocardial angiogenesis.
MedLine Citation:
PMID:  17950369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Armed with an improved understanding of the mediators of angiogenesis, physicians and scientists have made significant efforts at harnessing this naturally occurring process in order to treat patients with a variety of peripheral vascular and coronary ischemic syndromes. There is a growing population of patients with end-stage coronary artery disease (CAD) who are no longer candidates for mechanical revascularization, yet suffer from chronic myocardial ischemia who may benefit from regeneration of the depleted microvasculature.
Authors:
Marie-Ange Renault; Douglas W Losordo
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-09-07
Journal Detail:
Title:  Microvascular research     Volume:  74     ISSN:  0026-2862     ISO Abbreviation:  Microvasc. Res.     Publication Date:    2007 Sep-Nov
Date Detail:
Created Date:  2007-11-12     Completed Date:  2008-01-08     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  0165035     Medline TA:  Microvasc Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-71     Citation Subset:  IM    
Affiliation:
Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave., Tarry 12-703, Chicago, IL 60611, USA.
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MeSH Terms
Descriptor/Qualifier:
Angiogenesis Inducing Agents / pharmacology*,  therapeutic use*
Animals
Clinical Trials, Phase I as Topic
Clinical Trials, Phase II as Topic
Forecasting
Gene Transfer Techniques
Genetic Therapy / methods
Humans
Myocardial Ischemia / drug therapy*
Myocardial Revascularization / methods*
Neovascularization, Physiologic / physiology
Tissue Therapy / methods
Grant Support
ID/Acronym/Agency:
R01 HL057516-05/HL/NHLBI NIH HHS; R01 HL057516-06/HL/NHLBI NIH HHS; R01 HL057516-07/HL/NHLBI NIH HHS; R01 HL057516-08/HL/NHLBI NIH HHS; R01 HL057516-09/HL/NHLBI NIH HHS; R01 HL057516-10/HL/NHLBI NIH HHS; R01 HL057516-11/HL/NHLBI NIH HHS; R01 HL063414-01/HL/NHLBI NIH HHS; R01 HL063414-02/HL/NHLBI NIH HHS; R01 HL063414-03/HL/NHLBI NIH HHS; R01 HL063414-04/HL/NHLBI NIH HHS; R01 HL063414-05A1/HL/NHLBI NIH HHS; R01 HL063414-06/HL/NHLBI NIH HHS; R01 HL063414-07/HL/NHLBI NIH HHS; R01 HL063414-08/HL/NHLBI NIH HHS; R01 HL077428-01A2/HL/NHLBI NIH HHS; R01 HL077428-02/HL/NHLBI NIH HHS; R01 HL080137-01A1/HL/NHLBI NIH HHS; R01 HL080137-02/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Angiogenesis Inducing Agents
Comments/Corrections

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