| Therapeutic methods used in patients with Eisenmenger syndrome. | |
| | |
MedLine Citation:
|
PMID: 19950085 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Patients with Eisenmenger syndrome form a small percentage of congenital heart disease patients. The rarity of this syndrome, combined with its complex pathophysiology, account for the insufficient understanding of the principles underlying its proper treatment. The main clinical symptoms are: cyanosis due to secondary erythrocytosis, resulting in increased blood viscosity, iron deficiency anemia (enhanced by unnecessary phlebotomies), blood clotting disturbances, heart failure and serious supraventricular and ventricular arrhythmias. Recent decades have seen developments in pulmonary hypertension pathophysiology which have led to the introduction of new groups of drugs: prostacycline analogs (Epoprostenol, Treprostinil, Beraprost, Illoprost), phosphodiesterase inhibitors (Sildenafil, Tadalafil), endothelin receptor antagonists (Bosentan, Sitaxantan, Ambrisentan) and nitric oxide. These drugs should be administered to patients in III-IV NYHA class. Despite successful early results, the therapeutic effect on patients with Eisenmenger syndrome has not been conclusively established. Our therapeutic efforts should be directed mainly towards preventing complications. As a rule, we should avoid agents with no established therapeutic efficacy and try to alleviate symptoms without any additional risk, so as not to disrupt the existing clinical balance. |
| | |
Authors:
|
Olga Trojnarska; Karolina Plaskota |
Related Documents
:
|
15882735 - Evaluation and management of genital anomalies in two patients with klinefelter syndrom... 8331355 - Paroxysmal alien hand syndrome. 12907215 - Evaluation of tumour markers in patients with burning mouth syndrome. 3625195 - Platelet mao in patients with idiopathic pain disorders. 10411425 - Photosensitivity in the smith-lemli-opitz syndrome: the us experience of a new congenit... 16915905 - Tubulointerstitial nephritis and uveitis syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Cardiology journal Volume: 16 ISSN: 1897-5593 ISO Abbreviation: - Publication Date: 2009 |
Date Detail:
|
Created Date: 2009-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101392712 Medline TA: Cardiol J Country: Poland |
Other Details:
|
Languages: eng Pagination: 500-6 Citation Subset: IM |
Affiliation:
|
1st Cardiology Department, University of Medical Sciences, Poznań, Poland. olgatroj@wp.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiac transplantation is still the method of choice in the treatment of patients with severe heart...
Next Document: Relationship between echocardiographic parameters and exercise test duration in patients after myoca...