| Therapeutic management of type 1 diabetes before and during pregnancy. | |
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MedLine Citation:
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PMID: 21329488 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Introduction: Pregnancy increases the risks of adverse outcomes for mother and infant in women with type 1 diabetes. Obtaining and maintaining adequate glycemic control during pregnancy is crucial for optimizing outcomes. Areas covered: The importance of prepregnancy planning and treatment during pregnancy is reviewed. The use of insulin analogues and antihypertensive drugs in diabetic pregnancy are in focus. The reader is presented with evidence discussing the importance of prepregnancy counseling and treatment during pregnancy in women with type 1 diabetes. Expert opinion: Tight glycemic control before and during pregnancy is crucial and the prevalence of severe hypoglycemia during pregnancy needs to be reduced. Rapid-acting insulin analogues are regarded as safe to use in pregnancy and studies on long-acting insulin analogues are in the pipeline. Supplementation with folic acid may reduce the risk of malformations. Screening for diabetic retinopathy, diabetic nephropathy and thyroid dysfunction is important, and indications for antihypertensive treatment and treatment of thyroid dysfunction need to be in focus before and during pregnancy. |
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Authors:
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Elisabeth R Mathiesen; Lene Ringholm; Peter Damm |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-18 |
Journal Detail:
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Title: Expert opinion on pharmacotherapy Volume: - ISSN: 1744-7666 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100897346 Medline TA: Expert Opin Pharmacother Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University of Copenhagen, Center for Pregnant Women with Diabetes, Department of Endocrinology and Obstetrics, Faculty of Health Science, 2132, Rigshospitalet, Blegdamsvej 9, DK 2100, Copenhagen Ø, Denmark +45 35458358 ; em@rh.dk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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