Document Detail


Therapeutic lifestyle changes and pharmaceutical care in the treatment of dyslipidemias in adults.
MedLine Citation:
PMID:  16128506     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To review each therapeutic lifestyle change (TLC) component listed in the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) cholesterol guidelines and discuss how the guidelines can be used by pharmacists in the treatment of patients with dyslipidemias. DATA SOURCES: Published guidelines and abstracts identified through PubMed (May 1987-March 2004), Medline (January 1966-March 2004), using the search terms cholesterol, hypercholesterolemia, dyslipidemia, hyperlipidemia, diet, saturated fats, unsaturated fats, trans-fatty acids, overweight, obese, exercise, physical activity, program adherence, and guidelines; as well as the NCEP ATP III guidelines, the 2004 ATP III update, National Heart, Lung, and Blood Institute Obesity Guidelines, and Dietary Guidelines for Americans 2005. STUDY SELECTION: Performed manually by author. DATA EXTRACTION: Performed manually by author. DATA SYNTHESIS: TLC components are recommended in the NCEP ATP III guidelines for treatment of patients with dyslipidemias independent of medication use. Dietary modifications are the primary focus of TLC therapy. Saturated fat intake should be limited to less than 7% of total caloric intake and trans-fatty acid intake should be low for patients with dyslipidemias. Persons who are overweight or obese with dyslipidemias should reduce body weight through a combination of physical activity, total calorie reduction, and behavior therapy modifications. CONCLUSION: Pharmacists, given the proper training, can be effective at offering preventive pharmaceutical care for decreasing high blood cholesterol and the risk for coronary heart disease through patient counseling on TLC components as well as drug therapy in patients with dyslipidemias.
Authors:
Thomas L Lenz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American Pharmacists Association : JAPhA     Volume:  45     ISSN:  1544-3191     ISO Abbreviation:  J Am Pharm Assoc (2003)     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-08-30     Completed Date:  2006-05-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101176252     Medline TA:  J Am Pharm Assoc (2003)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  492-9; quiz 500-2     Citation Subset:  IM    
Affiliation:
Department of Pharmacy Practice, School of Pharmacy and Health Professions, Creighton University Medical Center, 2500 California Plaza, Omaha, NE 68178, USA. tlenz@creighton.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Community Pharmacy Services / standards*,  trends
Dyslipidemias / therapy*
Education, Pharmacy, Continuing
Humans
Life Style*
Pharmaceutical Services / standards*,  trends
Practice Guidelines as Topic / standards

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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