Document Detail


Therapeutic efficacy and complications of excisional biopsy of condyloma acuminatum.
MedLine Citation:
PMID:  8836019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVES: Among the various treatment modalities for condyloma acuminatum, excisional cold-blade surgery appears excellent but it has been little studied and little used, particularly for lesions not located in the perianal area. GOALS: To examine the efficacy and complications of scissors excision of single anogenital warts. STUDY DESIGN: Retrospective analysis of single warts completely excised with scissors for the purpose of biopsy before patient entry in a randomized, placebo-controlled study of the efficacy and safety of various parenteral interferons in combination with cryotherapy. RESULTS: Of 152 patients entered in the main study, 85 patients were available for analysis. At 4 and 16 weeks after excision, 16 of 85 (19%) and 14 of 68 (21%) of the excised lesions recurred. After at 6 least months of follow-up, 2 of 11 (18%) of the excision sites demonstrated some evidence of pigmentation changes. CONCLUSIONS: Scissors excision of single anogenital warts has a high rate of success and acceptable long-term side-effects.
Authors:
W Bonnez; D Oakes; A Choi; S J d'Arcy; P G Pappas; L Corey; M H Stoler; L M Demeter; R C Reichman
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Sexually transmitted diseases     Volume:  23     ISSN:  0148-5717     ISO Abbreviation:  Sex Transm Dis     Publication Date:    1996 Jul-Aug
Date Detail:
Created Date:  1996-12-13     Completed Date:  1996-12-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7705941     Medline TA:  Sex Transm Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  273-6     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Rochester, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiviral Agents / therapeutic use
Biopsy* / adverse effects,  methods
Combined Modality Therapy
Condylomata Acuminata / etiology,  pathology*,  surgery*
Cryosurgery
Female
Humans
Interferons / therapeutic use
Male
Recurrence
Retrospective Studies
Risk Factors
Treatment Outcome
Grant Support
ID/Acronym/Agency:
AI-82509/AI/NIAID NIH HHS; RR00044/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Antiviral Agents; 9008-11-1/Interferons

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