Document Detail

Therapeutic effects of laser photocoagulation and/or vitrectomy in Eales' disease.
MedLine Citation:
PMID:  15945008     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine visual outcomes and regression of retinal neovascularization following laser photocoagulation and/or vitrectomy in eyes with Eales' disease. METHODS: In a retrospective noncomparative study, the authors reviewed the existing data of 67 eyes of 54 patients with a diagnosis of Eales' disease who had undergone laser photocoagulation and/or vitrectomy based on their clinical presentations. Main outcome measures were visual acuity changes and regression of retinal neovascularization of the eyes following treatment. RESULTS: Both laser therapy and vitrectomy improved visual acuity and induced regression of retinal neovascularization. Forty-three eyes had undergone laser therapy; their rate of visual acuity 320/30 improved from 53% before treatment to 60% after treatment. Twenty-four eyes had undergone vitrectomy; rate of visual acuity 320/30 improved from 13% before surgery to 38% after surgery. In eyes that had undergone laser therapy, additional laser therapy controlled recurrent neovascularization in 47% of the eyes, but ultimately, 12% of them required vitrectomy. In the primary vitrectomized group, additional required treatment was repeat vitrectomy in 21%, and/or laser therapy in 29% of the eyes. CONCLUSIONS: Although laser photocoagulation should be the first line of treatment in Eales' disease, it cannot always induce regression of retinal neovascularization. In such cases vitrectomy may further enhance therapeutic success.
M H Dehghan; H Ahmadieh; M Soheilian; M Azarmina; A Mashayekhi; J Naghibozakerin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  15     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-06-09     Completed Date:  2005-08-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  379-83     Citation Subset:  IM    
Department of Ophthalmology and Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
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MeSH Terms
Fluorescein Angiography
Follow-Up Studies
Fundus Oculi
Laser Coagulation*
Middle Aged
Recurrence / prevention & control
Retinal Neovascularization / physiopathology
Retinal Vasculitis / complications,  pathology,  surgery*
Retrospective Studies
Treatment Outcome
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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