Document Detail


Therapeutic effects of laser photocoagulation and/or vitrectomy in Eales' disease.
MedLine Citation:
PMID:  15945008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine visual outcomes and regression of retinal neovascularization following laser photocoagulation and/or vitrectomy in eyes with Eales' disease. METHODS: In a retrospective noncomparative study, the authors reviewed the existing data of 67 eyes of 54 patients with a diagnosis of Eales' disease who had undergone laser photocoagulation and/or vitrectomy based on their clinical presentations. Main outcome measures were visual acuity changes and regression of retinal neovascularization of the eyes following treatment. RESULTS: Both laser therapy and vitrectomy improved visual acuity and induced regression of retinal neovascularization. Forty-three eyes had undergone laser therapy; their rate of visual acuity 320/30 improved from 53% before treatment to 60% after treatment. Twenty-four eyes had undergone vitrectomy; rate of visual acuity 320/30 improved from 13% before surgery to 38% after surgery. In eyes that had undergone laser therapy, additional laser therapy controlled recurrent neovascularization in 47% of the eyes, but ultimately, 12% of them required vitrectomy. In the primary vitrectomized group, additional required treatment was repeat vitrectomy in 21%, and/or laser therapy in 29% of the eyes. CONCLUSIONS: Although laser photocoagulation should be the first line of treatment in Eales' disease, it cannot always induce regression of retinal neovascularization. In such cases vitrectomy may further enhance therapeutic success.
Authors:
M H Dehghan; H Ahmadieh; M Soheilian; M Azarmina; A Mashayekhi; J Naghibozakerin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  15     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-06-09     Completed Date:  2005-08-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  379-83     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology and Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. mhdehghan5@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fluorescein Angiography
Follow-Up Studies
Fundus Oculi
Humans
Laser Coagulation*
Male
Middle Aged
Recurrence / prevention & control
Retinal Neovascularization / physiopathology
Retinal Vasculitis / complications,  pathology,  surgery*
Retrospective Studies
Treatment Outcome
Visual Acuity
Vitrectomy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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