Document Detail

Therapeutic effects of endoscopic variceal ligation combined with partial splenic embolization for portal hypertension.
MedLine Citation:
PMID:  15052697     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the feasibility of a new strategy of endoscopic variceal ligation combined with partial splenic embolization (EVL-PSE) for patients with cirrhosis and portal hypertension. METHODS: From May 1999 to May 2002, 41 cases with cirrhosis and portal hypertension underwent EVL-PSE. Hemodynamics of the main portal vein (MPV), the left gastric vein (LGV) and azygos vein, including maximum velocity, flow rate and vein diameter, were assessed by Doppler ultrasonography. RESULTS: One case died from pulmonary artery embolism. One case complicated with splenic abscess was successfully managed by laparotomy. The esophageal varices and hypersplenism were well controlled after EVL-PSE in other patients. After EVL-PSE, the flow rate and velocity of MPV was significantly reduced (P<0.05), as well as the flow rate of the LGV and azygos vein. During the follow-up, no recurrent bleeding was found. CONCLUSION: Being more convenient and less invasive, EVL-PSE is hopeful to be a proper intervention strategy for portal hypertensive patients with impaired hepatic function or those intolerant to shunting or devascularization surgery.
Rui-Yun Xu; Bo Liu; Nan Lin
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  10     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-30     Completed Date:  2004-05-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1072-4     Citation Subset:  IM    
Department of General Surgery, The Third Affiliated Hospital, Sun-Yet-San University, Guangzhou 510630, Guangdong Province, China.
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MeSH Terms
Embolization, Therapeutic*
Endoscopy, Digestive System*
Esophageal and Gastric Varices / surgery*
Feasibility Studies
Hypertension, Portal / complications,  therapy*
Liver Cirrhosis / complications
Middle Aged
Spleen / blood supply*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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