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Therapeutic effect of topical ozonated oil on the epithelial healing of palatal wound sites: a planimetrical and cytological study.
MedLine Citation:
PMID:  25426896     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
AIM:   To evaluate the effect of ozonated oil on palatal wounds.
METHODS:   Eighteen patients were randomized and allocated to either the ozone group (n = 8) or control (n = 10) group. Free gingival graft surgery was performed, and post-harvested palatal wounds were treated with either 2 mL ozonated oil or control oil daily for 1 week. A planimetrical analysis analyzed the digital image for the wound sizes and shape factor at baseline, at 24 h, and days 5, 7, 14, 21, and 28, postoperatively. A cytological analysis used the keratinization and superficial cell indices at baseline, 24 h, and days 3, 7, 14, and 21 and the second and third months, postoperatively.
RESULTS:   Planimetrical results showed a significant (P ≤ 0.05) improvement in wound size on days 5, 7, 14, 21, and 28, postoperatively, in the ozone group compared to the control group. Cytological results showed a significant (P ≤ 0.001) improvement in epithelial healing on days 7, 14, and 21, and the second and third months, postoperatively, after the application of ozonated oil compared to control oil.
CONCLUSION:   Our results showed significant improvement in wound size and epithelial healing after topical ozonated oil application compared to control oil on palatal wounds.
Authors:
Punit Vaibhav Patel; Veerendra Kumar; Sheela Kumar; Vidya Gd; Amrita Patel
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Publication Detail:
Type:  Journal Article     Date:  2011-07-07
Journal Detail:
Title:  Journal of investigative and clinical dentistry     Volume:  2     ISSN:  2041-1626     ISO Abbreviation:  J Investig Clin Dent     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2014-11-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101524471     Medline TA:  J Investig Clin Dent     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  248-58     Citation Subset:  D; IM    
Copyright Information:
© 2011 Blackwell Publishing Asia Pty Ltd.
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