Document Detail


Therapeutic approaches to malnutrition in chronic dialysis patients: the different modalities of nutritional support.
MedLine Citation:
PMID:  9915288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Protein-energy malnutrition (PEM) is a common complication in maintenance hemodialysis and chronic peritoneal dialysis patients and is a powerful predictor of morbidity and mortality. Although this association does not prove that malnutrition is a cause of this increased morbidity and mortality, it is consistent with this possibility. There are a number of modalities of nutritional support for the prevention or treatment of PEM in maintenance dialysis patients. Routine methods include preventing PEM before the onset of maintenance dialysis therapy, dietary counseling, maintenance of an adequate dose of dialysis, avoidance of acidemia, and aggressive treatment of superimposed catabolic illness. Specific treatments of chronic dialysis patients who have persistently inadequate nutritional intake include food supplements, enteral tube feeding, intradialytic parenteral nutrition, and total parenteral nutrition. More experimental forms of nutritional therapy include dialytic nutrition (eg, using peritoneal dialysate or hemodialysate that contains amino acids), appetite stimulants (eg, megestrol acetate), or growth factors (eg, anabolic steroids, recombinant human growth hormone, or insulin-like growth factor-I).
Authors:
J D Kopple
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  33     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-02-04     Completed Date:  1999-02-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  180-5     Citation Subset:  IM    
Affiliation:
Division of Nephrology and Hypertension, Harbor-UCLA Medical Center and Schools of Medicine and Public Health, UCLA, Los Angeles, CA 90509, USA. kopple@afp76.humc.edu
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MeSH Terms
Descriptor/Qualifier:
Humans
Kidney Failure, Chronic / complications,  therapy*
Nutritional Support / methods*
Protein-Energy Malnutrition / etiology,  therapy*
Renal Dialysis / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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