| Therapeutic approach in patients with stable angina. | |
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MedLine Citation:
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PMID: 15773267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Which therapeutic strategy among medical, interventional and surgical options should be preferred in patients with chronic stable ischemic heart disease is an important public health problem. The available scientific evidence does not help much to facilitate the choice among the three available strategies of medical treatment, percutaneous coronary intervention and coronary artery bypass grafting. In this area practice-based medicine overwhelms evidence-based medicine. However, existing findings are discussed. The present experience in diabetic patients is highlighted; in such patients surgery is generally recommended but the results obtained by percutaneous coronary intervention with the currently available tools are improving markedly. Pharmacological therapy is also improving, particularly in the prevention of the progression of atherothrombosis and consequently of cardiovascular events. Actually two categories of drugs should be recognized: those prescribed to prevent death and myocardial infarction and those with antianginal and anti-ischemic effects aimed at alleviating symptoms and reducing ischemia. The first group of drugs includes antiplatelet-antithrombotic agents, lipid-lowering agents and angiotensin-converting enzyme inhibitors; the second group includes beta-blockers, calcium antagonists and nitrates. A good integration of the two classes of drugs, combined with an appropriate use of coronary revascularization procedures, should yield the maximum possible benefit in the individual patient. |
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Authors:
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Maddalena Lettino; Colomba Falcone; Luigi Tavazzi |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Italian heart journal : official journal of the Italian Federation of Cardiology Volume: 6 ISSN: 1129-471X ISO Abbreviation: Ital Heart J Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-03-18 Completed Date: 2005-06-09 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100909716 Medline TA: Ital Heart J Country: Italy |
Other Details:
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Languages: eng Pagination: 1-8 Citation Subset: IM |
Affiliation:
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Coronary Care Unit, IRCCS San Matteo Hospital, Pavia, Italy. m.lettino@smatteo.pv.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use Angina Pectoris / therapy* Angioplasty, Transluminal, Percutaneous Coronary Angiotensin-Converting Enzyme Inhibitors / therapeutic use Antilipemic Agents / therapeutic use Calcium Channel Blockers / therapeutic use Chronic Disease Coronary Artery Bypass Coronary Thrombosis / prevention & control Decision Making Fibrinolytic Agents / therapeutic use Humans Myocardial Revascularization / methods* Platelet Aggregation Inhibitors / therapeutic use Vasodilator Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Antilipemic Agents; 0/Calcium Channel Blockers; 0/Fibrinolytic Agents; 0/Platelet Aggregation Inhibitors; 0/Vasodilator Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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