Document Detail


Therapeutic ultrasound-enhanced thrombolysis in patients with acute myocardial infarction.
MedLine Citation:
PMID:  19926625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thrombolytic therapy is widely used to treat the patients with ST elevation acute myocardial infarction (STE-MI). Due to logistic and economic reasons, only 10% of patients with acute myocardial infarction can be treated with the percutaneous coronary intervention (PCI). Optimal flow (TIMI (Thrombolysis In Myocardial Infarction) 3 flow) is achieved in only about 60% of cases by enzymatic thrombolysis. Therapeutic ultrasound (US) exerts an effect on thrombolysis by micromechanical processes or indirectly by supporting enzymatic thrombolysis. This review examines relevant experimental and clinical published data. Technical issues in therapeutic US-enhanced thrombolysis in patients with acute myocardial infarction and advancements of the techniques during recent 10 years are discussed.
Authors:
Xuedong Shen; Chandra Nair; Mark Holmberg; Aryan Mooss; Amy Arouni; Dennis Esterbrooks
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-11-18
Journal Detail:
Title:  Angiology     Volume:  61     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-06-07     Completed Date:  2010-06-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  253-8     Citation Subset:  IM    
Affiliation:
Department of Cardiology, The Cardiac Center of Creighton University, Omaha, Nebraska, USA. xshen@cardiac.creighton.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Heart Catheterization
Humans
Myocardial Infarction / therapy*
Thrombolytic Therapy / methods*
Ultrasonic Therapy / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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