Document Detail


Therapeutic strategies of meconium obstruction of the small bowel in very-low-birthweight neonates.
MedLine Citation:
PMID:  20735806     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background:  Meconium obstruction without cystic fibrosis in low-birthweight neonates is a distinct clinical entity. We aimed to determine what therapeutic strategies work best in very-low-birthweight neonates with meconium obstruction of the small bowel under varied clinical conditions caused by the associated diseases of prematurity. Methods:  Medical records of very-low-birthweight neonates with meconium obstruction of the small bowel treated from 1998 to 2008 were retrospectively reviewed. Pre- and postnatal data, treatments, and clinical outcomes were assessed. Results:  Nine patients with perinatal complications were identified. Mean gestational age and birthweight were 26.9 weeks and 863 g, respectively. Abdominal distension developed from 1 to 7 days of life. Five patients were initially treated with Gastrografin enema, three of whom had successful outcomes. Two hemodynamically unstable patients failed to respond to Gastrografin treatment; they ultimately died of sepsis. The remaining four without Gastrografin treatment underwent enterostomy to resolve the obstructions with good results. Conclusions:  Gastrografin and surgical treatments should be appropriately selected based on the underlying pathologies of meconium obstruction of the small bowel. Therapeutic Gastrografin enema is effective, safe and repeatable; however, it is not recommended for hemodynamically unstable patients. Surgical intervention is reserved for those who develop rapid abdominal distension that risks perforation.
Authors:
Tsugumichi Koshinaga; Mikiya Inoue; Kensuke Ohashi; Kiminobu Sugito; Taro Ikeda; Ryouichi Tomita
Related Documents :
17267306 - Multichannel intraluminal impedance to detect relationship between gastroesophageal ref...
1621466 - Comparison of staple and gambee techniques for enterotomy closure in the normal bovine ...
23126546 - Inhaled nitric oxide in preterm infants.
21238706 - Oxygen supplementation in the delivery room: updated information.
11534636 - Population dynamics of ornithodiplostomum ptychocheilus metacercariae in fathead minnow...
22341556 - Comparing icd-9 and icd-10: the impact on intentional and unintentional injury mortalit...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  53     ISSN:  1442-200X     ISO Abbreviation:  Pediatr Int     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-06-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  338-44     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors.Pediatrics International © 2011 Japan Pediatric Society.
Affiliation:
Department of Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Children treated for epileptic encephalopathies show improved glucose metabolism.
Next Document:  Prophylactic treatment for hypertension and seizure in a case of allogeneic hematopoietic stem cell ...