Document Detail

Theory and methods of local tissue-pO2 monitoring in experimental angiology.
MedLine Citation:
PMID:  3813118     Owner:  NLM     Status:  MEDLINE    
The platinum-multiwire-surface electrode after Kessler and Lübbers gives the opportunity of direct measuring of the local tissue-pO2-pressure; this 8-wire electrode with a Pt-wire-diameter of 15 microns operates on the polarographic principle. Each Pt-wire has a hemispheric collecting area of about 30 microns. Pressure ischemia by compression of capillaries is prevented by proportioning the weight (2.1 g) of the electrode. Data output is done by continuous pO2 measuring; pO2 histograms. During the continuous pO2 measurement the electrode stays on the tissue measuring point thus enabling the direct record of quickly proceeding reactions. The pO2-histogram exhibits the statistical distribution of the local partial oxygen pressures in a studied organ, a quasi sample inquiry is performed in the tissue, based on minimum 100 single values that are obtained by repeated manual repositioning of the electrode. By this, values are obtained on the level and distribution of local pO2 in the tissue so that condition and function of the microcirculation can be objectively assessed. Immediate alterations in the local tissue pO2 suggest regulatory adjustment after hemodynamic changes. Technical problems connected with pO2 measurement in clinical use (sterilization, data acquisition and presentation) are described. The presented technique gives the chance to exactly assess the effects of vasoactive drugs on the microcirculation and to quantify the results of operations, for example after bypass-surgery.
H U Spiegel; J Hauss; K Schönleben; H Bünte
Related Documents :
17437498 - Comparing oxygen transfer performance between three membrane oxygenators: effect of tem...
17566188 - Effects of oxygen therapy on left ventricular function in patients with cheyne-stokes r...
18250118 - Impaired autoregulation in preterm infants identified by using spatially resolved spect...
7232268 - Representative oxygen dissociation curve and equation for the chicken.
4021438 - Pulmonary physiology of the ferret and its potential as a model for inhalation toxicology.
12064958 - Ambulatory blood pressure monitoring.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angiology     Volume:  38     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1987 Jan 
Date Detail:
Created Date:  1987-03-18     Completed Date:  1987-03-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-12     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anoxia / physiopathology
Blood Vessels / physiology*
Capillaries / physiology
Monitoring, Physiologic
Oxygen / physiology*
Partial Pressure
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Clinical experience with a new rate-responsive TX pacemaker.
Next Document:  The influence of R-wave amplitude on the degree of ST-segment depression in exercise electrocardiogr...