| Theory of cell age distribution in suspension culture with feed and/or drain. | |
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MedLine Citation:
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PMID: 2520206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A mixed problem for the M'Kendrick-von Foerster equation satisfied by the number density function in terms of the age of the viable cells in a suspension culture with feed and/or drain is solved, and a method of calculating the number density function and time-dependent generation time from observed data of cell number and cell mass is presented. This theory is adequate to analyze the growth of cells that undergo binary fission. The equation of mass balance follows as a natural consequence of this treatment. The equation of substrate balance in consideration of the effect of cell volume is derived rigorously. |
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Authors:
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H Funakoshi; A Yamada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Mathematical biosciences Volume: 97 ISSN: 0025-5564 ISO Abbreviation: Math Biosci Publication Date: 1989 Nov |
Date Detail:
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Created Date: 1992-04-20 Completed Date: 1992-04-20 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0103146 Medline TA: Math Biosci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 61-83 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Aging* Cell Count Cell Division Cells, Cultured Mathematics Models, Biological |
| Comments/Corrections | |
Erratum In:
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Math Biosci 1990 Apr;99(1):141 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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