| Theoretical and experimental approach to recognition of amino acid by tRNA. | |
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MedLine Citation:
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PMID: 6664848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The C4N model concludes that the pocket on the complex of the anticodon bases and the discriminator base on a tRNA can accept the corresponding protein amino acid. A theoretical molecular computation by using the energy minimum principle is carried out to find the energy-refined C4N conformation. The results for Gln and Val suggest that not only the lock and key relationship but the induced fitting effect occurs. Some experiments to detect the interaction between the polynucleotides and the amino acid are being attempted. |
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Authors:
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S Yoneda; M Shimizu; N Go; S Fujii; M Uchida; K Miura; K Watanabe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nucleic acids symposium series Volume: - ISSN: 0261-3166 ISO Abbreviation: Nucleic Acids Symp. Ser. Publication Date: 1983 |
Date Detail:
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Created Date: 1984-03-16 Completed Date: 1984-03-16 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 8007206 Medline TA: Nucleic Acids Symp Ser Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 145-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids* Genetic Code* Models, Molecular Nucleic Acid Conformation RNA, Transfer* Thermodynamics |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 9014-25-9/RNA, Transfer |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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