| Thematic review series: patient-oriented research. Dietary fat, carbohydrate, and protein: effects on plasma lipoprotein patterns. | |
| | |
MedLine Citation:
|
PMID: 16738356 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In general, under isoweight conditions, different types of dietary protein or individual amino acids have little effect on lipoprotein patterns. Dietary carbohydrate tends to increase plasma triglyceride when it displaces fat, accompanied by a decrease in HDL cholesterol concentrations. Potential differential effects of types of carbohydrate are difficult to assess because of differences in rates of absorption and confounding of dietary fiber. Saturated fatty acids increase LDL and HDL cholesterol, whereas trans fatty acids increase LDL but not HDL cholesterol. Unsaturated fatty acids decrease LDL and HDL cholesterol, polyunsaturated more so than monounsaturated. There has been considerable interest in the potential benefit of major shifts in dietary macronutrients on weight loss and lipoprotein patterns. Short-term data favor substituting protein and fat for carbohydrate, whereas long-term data have failed to show a benefit for weight loss. During an active weight loss period low-carbohydrate diets more favorably affect triglyceride and HDL and less favorably affect LDL cholesterol concentrations. Additional efforts need to be focused on gaining a better understanding of the effect of dietary macronutrient profiles on established and emerging cardiovascular disease risk factors, mechanisms for changes observed and contributors to individual variability. Such data are needed to allow reassessment and, if necessary, modification of current recommendations. |
| | |
Authors:
|
Alice H Lichtenstein |
Related Documents
:
|
9500566 - Increased activity of lecithin:cholesterol acyltransferase during short-term oral estro... 14566456 - Hdl-cholesterol level and cortisol response to synacthen in critically ill patients. 8310996 - Pyruvate supplementation of a low-cholesterol, low-fat diet: effects on plasma lipid co... 8892766 - Changes in plasma lipids and lipoproteins associated with starting or stopping postmeno... 6832106 - Effects of zinc on cadmium-induced alterations in hepatic functions and blood glucose o... 20875836 - Selenium or selenium plus folic acid intake improves the detrimental effects of ethanol... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review Date: 2006-05-31 |
Journal Detail:
|
Title: Journal of lipid research Volume: 47 ISSN: 0022-2275 ISO Abbreviation: J. Lipid Res. Publication Date: 2006 Aug |
Date Detail:
|
Created Date: 2006-08-02 Completed Date: 2006-09-26 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0376606 Medline TA: J Lipid Res Country: United States |
Other Details:
|
Languages: eng Pagination: 1661-7 Citation Subset: IM |
Affiliation:
|
Cardiovascular Nutrition Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. alice.lichtenstein@tufts.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Body Weight
/
drug effects Cardiovascular Diseases / blood Dietary Carbohydrates / administration & dosage* Dietary Fats / administration & dosage* Humans Lipoproteins / blood* Triglycerides / blood |
| Grant Support | |
ID/Acronym/Agency:
|
HL-54727/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Carbohydrates; 0/Dietary Fats; 0/Lipoproteins; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of a routine mental health measure in an adolescent secure unit.
Next Document: Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipo...