Document Detail

Thallium-201 myocardial imaging in anomalous left coronary artery arising from the pulmonary artery. Applications before and after medical and surgical treatment.
MedLine Citation:
PMID:  696649     Owner:  NLM     Status:  MEDLINE    
Thallium-201 myocardial imaging was performed on six patients with an anomalous left coronary artery arising from the pulmonary artery. Initial images in three children (aged 4 months, 12 months and 2 1/2 years, respectively) demonstrated anterolateral perfusion defects in agreement with the electrocardiographic localization of infarction. Repeat imaging in two patients 2 to 3 months later, after clinical improvement with anticongestive therapy, demonstrated a reduction in the perfusion defect. In 3 other patients (aged 16, 16 and 20 years, respectively) thallium-201 scans performed during exercise stress demonstrated normal myocardial perfusion 7 to 15 years after operation (ligation of anomalous left coronary in two, ligation plus bypass graft in one). Thallium-201 imaging appears to be helpful in monitoring changes in myocardial perfusion before and after medical or surgical treatment of an anomalous left coronary artery, and may shed light on the pathophysiology of the defect. A possible practical limitation of thallium-201 imaging in this condition is the difficulty of imaging subendocardial infarction.
J P Finley; R Howman-Giles; D L Gilday; P M Olley; R D Rowe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  42     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1978-11-22     Completed Date:  1978-11-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  675-80     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Coronary Vessel Anomalies / complications,  radionuclide imaging*,  surgery
Coronary Vessels / surgery
Digoxin / therapeutic use
Evaluation Studies as Topic
Follow-Up Studies
Heart Failure / drug therapy,  etiology
Physical Exertion
Pulmonary Artery / abnormalities*
Radioisotopes / diagnostic use*
Thallium / diagnostic use*
Reg. No./Substance:
0/Radioisotopes; 20830-75-5/Digoxin; 7440-28-0/Thallium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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