Document Detail


Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study.
MedLine Citation:
PMID:  15580219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirteen children with difficult systemic onset juvenile rheumatoid arthritis were treated with thalidomide. At 6 months, 11 of the 13 were able to reduce their use of prednisone ( P < .002), with a concurrent improvement in erythrocyte sedimentation rate ( P < .0001) and an increase in hemoglobin level ( P < 0.005). Juvenile rheumatoid arthritis improvement scores >/=50% were obtained by 10 of the 13 children.
Authors:
Thomas J A Lehman; Sharon J Schechter; Robert P Sundel; Sheila K Oliveira; Anna Huttenlocher; Karen B Onel
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  145     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-12-06     Completed Date:  2005-01-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  856-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Pediatric Rheumatology, Hospital for Special Surgery, and the Department of Pediatrics, Sanford Weill Medical College of Cornell University, New York, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Juvenile Rheumatoid / drug therapy*
Blood Sedimentation / drug effects
Child
Female
Humans
Immunosuppressive Agents / therapeutic use*
Male
Thalidomide / therapeutic use*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 50-35-1/Thalidomide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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