Document Detail

Thalassemia and pregnancy.
MedLine Citation:
PMID:  12959481     Owner:  NLM     Status:  MEDLINE    
Thalassemia syndromes, hemoglobinopathies characterized by anemia secondary to genetic defects of hemoglobin, are the most common of the genetic blood disorders. The prevalence and severity of the thalassemia syndromes are population dependent, with the type of thalassemia seen dependent on racial background. The health care provider must recognize the woman at highest risk for thalassemia and initiate appropriate screening and diagnostic testing. The specific thalassemia dictates the potential maternal, fetal, and neonatal consequences of anemia, red blood cell dysfunction, and systemic oxygenation issues. This article discusses normal globin chain synthesis, diagnostic testing for thalassemia, plan of management, and implications for the woman and fetus.
Judith H Poole
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of perinatal & neonatal nursing     Volume:  17     ISSN:  0893-2190     ISO Abbreviation:  J Perinat Neonatal Nurs     Publication Date:    2003 Jul-Sep
Date Detail:
Created Date:  2003-09-08     Completed Date:  2003-10-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8801387     Medline TA:  J Perinat Neonatal Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  196-208     Citation Subset:  N    
Presbyterian Healthcare System, Presbyterian Hospital, Charlotte, NC 28233, USA.
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MeSH Terms
Chelation Therapy
Fetal Hemoglobin / genetics
Neonatal Nursing / methods
Nursing Methodology Research
Perinatal Care / methods
Pregnancy Complications, Hematologic / diagnosis,  nursing*
Prenatal Diagnosis / methods*
Thalassemia / diagnosis,  genetics,  nursing*
alpha-Thalassemia / nursing
beta-Thalassemia / nursing
Reg. No./Substance:
9034-63-3/Fetal Hemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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