| Thalamic contributions to Basal Ganglia-related behavioral switching and reinforcement. | |
| | |
MedLine Citation:
|
PMID: 22072662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although the existence of prominent connections between the intralaminar thalamic nuclei and the basal ganglia has long been established, the limited knowledge of the functional relevance of this network has considerably hampered progress in our understanding of the neural mechanisms by which the thalamostriatal system integrates and regulates the basal ganglia circuitry. In this brief commentary, we will address this gap of knowledge through a discussion of the key points of a symposium entitled "Thalamic Contributions to Basal Ganglia-Related Behavioral Switching and Reinforcement" that will be presented at the 2011 Society for Neuroscience meeting. Recent anatomical and physiological data that support the role of the thalamostriatal system in action selection, attentional shifting, and reinforcement will be discussed. We will also address the possibility that degeneration of the thalamostriatal system could underlie some of the deficits in redirection of attention in response to salient stimuli seen in Parkinson's disease. |
| | |
Authors:
|
Yoland Smith; D James Surmeier; Peter Redgrave; Minoru Kimura |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: The Journal of neuroscience : the official journal of the Society for Neuroscience Volume: 31 ISSN: 1529-2401 ISO Abbreviation: J. Neurosci. Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-10 Completed Date: 2012-01-04 Revised Date: 2012-05-11 |
Medline Journal Info:
|
Nlm Unique ID: 8102140 Medline TA: J Neurosci Country: United States |
Other Details:
|
Languages: eng Pagination: 16102-6 Citation Subset: IM |
Affiliation:
|
Yerkes National Primate Research Center and Department of Neurology, Emory University, Atlanta, Georgia 30329, USA. ysmit01@emory.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Attention / physiology* Basal Ganglia / cytology, physiology* Humans Neural Pathways / anatomy & histology, physiology Neurons / physiology Parkinson Disease / pathology, physiopathology Reinforcement (Psychology)* Thalamus / cytology, physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
P50 NS071669-02/NS/NINDS NIH HHS; R01 NS037948-12/NS/NINDS NIH HHS; R01 NS037948-15/NS/NINDS NIH HHS; R01 NS062876-03/NS/NINDS NIH HHS; //Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function.
Next Document: Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormones.