Document Detail


Thalamic amnesia: Korsakoff syndrome due to left thalamic infarction.
MedLine Citation:
PMID:  1506870     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to support the concept that a lesion of the thalamus is sufficient to cause a Korsakoff syndrome, we are presenting 5 patients, all of whom developed the syndrome after sustaining a left (dominant) thalamic infarction. Two patients had pure thalamic strokes followed by a permanent Korsakoff syndrome. One of these patients was studied with neuropsychometric testing, as well as with a modern MRI scan. In 2 other patients, clinical and imaging data indicate that infarction was not limited to the thalamus. Another patient had bilateral thalamic infarcts but only a temporary Korsakoff syndrome. Neuropathological data are needed to elucidate the exact anatomical substrate of dominant thalamic Korsakoff syndrome.
Authors:
M Cole; M D Winkelman; J C Morris; J E Simon; T A Boyd
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  110     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-09-23     Completed Date:  1992-09-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  62-7     Citation Subset:  IM    
Affiliation:
Department of Neurology, MetroHealth Medical Center, Cleveland, OH 44109.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alcohol Amnestic Disorder / complications,  pathology*,  physiopathology
Cerebral Infarction / complications,  pathology*
Female
Humans
Intelligence Tests
Magnetic Resonance Imaging
Middle Aged
Neuropsychological Tests
Thalamus / pathology*
Wechsler Scales

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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