Document Detail


Texture analysis of CT images in the characterization of oral cancers involving buccal mucosa.
MedLine Citation:
PMID:  22241875     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study was to investigate the usefulness of texture analysis in the characterization of oral cancers involving the buccal mucosa and to assess its effectiveness in differentiating between the various grades of the tumour.
METHODS: Contrast enhanced CT examination was carried out in 21 patients with carcinoma of the buccal mucosa who had consented to retrospective analysis during a research study that was approved by the institutional review board. Two regions of interest (ROIs) were created, one at the site of the lesion and the other at the contralateral normal side. Texture analysis measures of fractal dimension (FD), lacunarity and grey level co-occurrence matrix (GLCM) were computed for each ROI. The numeric data from the two ROIs were compared and were correlated with the tumour grade as confirmed by biopsy.
RESULTS: The difference between the mean FD and GLCM parameters of the lesion vs the normal ROI were statistically significant (p < 0.05); no significant difference was observed between the three grades of tumour for any of the parameters (p > 0.05).
CONCLUSION: Texture analysis on CT images is a potential method in the characterization of oral cancers involving the buccal mucosa and deserves further investigation as a predictor of tumour aggression.
Authors:
J V Raja; M Khan; V K Ramachandra; O Al-Kadi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-01-12
Journal Detail:
Title:  Dento maxillo facial radiology     Volume:  41     ISSN:  0250-832X     ISO Abbreviation:  Dentomaxillofac Radiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-07     Completed Date:  2012-11-01     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  7609576     Medline TA:  Dentomaxillofac Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  475-80     Citation Subset:  D    
Affiliation:
Department of Oral Medicine and Radiology, Dr Syamala Reddy Dental College Hospital and Research Centre, Bangalore, Karnataka, India. jigna.vr@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Contrast Media / diagnostic use
Female
Fractals
Humans
Male
Middle Aged
Mouth Mucosa / pathology*
Mouth Neoplasms / pathology,  radiography*
Neoplasm Grading
Radiographic Image Interpretation, Computer-Assisted / methods*
Retrospective Studies
Statistics, Nonparametric
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Contrast Media
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