Document Detail


Tetramine poisoning: A case report and review of the literature.
MedLine Citation:
PMID:  20678875     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Tetramethylene disulfotetramine (TETS), a banned neurotoxic rodenticide, has accounted for numerous intentional and unintentional poisonings in mainland China. Since the first known case of human illness caused by tetramine occurred in NewYork, in May 2002, TETS has caused more than 50 human poisonings in Western countries.
AIM: To analyze pathological changes of TETS poisoning and to provide evidence for forensic identification.
METHODS: We report the case of a 28-year-old female who suffered from tetramine poisoning and died of multi-organ failure. We also performed a retrospective study of 40 cases of poisoning, from pathological autopsy reports, by analyzing and summarizing the related the literature from 1996 to 2010. Based on pathologic autopsies and the literature, we summarize the pathological changes related to tetramine poisoning.
RESULTS: Signs of asphyxia were obvious upon pathological examination. Edema and congestion of organs, particularly in the brain, were seen in all cases. Subarachnoid and cerebral hemorrhaging were also common signs of tetramine poisoning.
CONCLUSION: In forensic practice, tetramine poisoning should be considered when the patient has signs of abnormal excitation of the central nervous system, convulsions, hyperspasmia, and cerebral hemorrhage.
Authors:
Ying Zhang; Min Su; Dong-Ping Tian
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Publication Detail:
Type:  Journal Article     Date:  2010-08-03
Journal Detail:
Title:  Forensic science international     Volume:  204     ISSN:  1872-6283     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e24-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Pathology, Shantou University Medical College, Shantou, Guangdong 515031, PR China.
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