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Tetralogy of Fallot: epidemiology meets real-world management: lessons from the Baltimore-Washington Infant Study.
MedLine Citation:
PMID:  24401260     Owner:  NLM     Status:  In-Data-Review    
Decades ago, mass-scale epidemiologic studies were undertaken to accurately describe the prevalence of congenital heart disease and associated malformations, and to identify inheritance patterns, teratogenic influence and aetiologic underpinnings. Despite phenomenal breakthroughs in molecular diagnosis of congenital heart disease, original population-based studies for detailed knowledge of prevalence, associated malformations, and appropriate patient and family counselling remain invaluable to the armamentarium and knowledge base of paediatric cardiologists. No modern-era studies have supplanted the importance of the Baltimore-Washington Infant Study undertaken from 1981 to 1989. In this article, we reprise the findings of the Baltimore-Washington Infant Study in tetralogy of Fallot, as well as to review current molecular diagnosis.
Melanie Nies; Joel I Brenner
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology in the young     Volume:  23     ISSN:  1467-1107     ISO Abbreviation:  Cardiol Young     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2014-01-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  866-9     Citation Subset:  IM    
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