Document Detail

Tetracycline-associated fatty liver of pregnancy, including possible pregnancy risk after chronic dermatologic use of tetracycline.
MedLine Citation:
PMID:  7230149     Owner:  NLM     Status:  MEDLINE    
Two cases of tetracycline-associated fatty liver of pregnancy are reported. In one, the history was negative for antibiotic use, yet autopsy revealed typical gross and microscopic bone fluorescence of tetracycline. Tissue extraction and chemical analysis showed qualitative evidence of tetracycline, whereas quantitation revealed 60 microgram/gm of wet bone tissue. Findings in our cases and in those from the literature indicate that the association of tetracycline use and fatty liver of pregnancy is even more common than has been suggested.
R E Wenk; F C Gebhardt; B S Bhagavan; J A Lustgarten; E F McCarthy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  26     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-07-09     Completed Date:  1981-07-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  135-41     Citation Subset:  IM    
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MeSH Terms
Fatty Liver / chemically induced*,  pathology
Liver / pathology
Pregnancy Complications / chemically induced*,  pathology
Tetracycline / adverse effects*,  therapeutic use
Reg. No./Substance:

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