Document Detail

Tetanus: study of 8,697 cases.
MedLine Citation:
PMID:  10710833     Owner:  NLM     Status:  MEDLINE    
Records of 8,697 cases of tetanus seen over a period of 14 years are analysed. Overall mortality was 48.0%. Mortality in neonatal group was 86.38% whereas that in non-neonatal group it was 40.18%. Disease was seen more frequently in male than in female. Mortality in male was lower than in female. Incidence was highest in the first decade of life. Mortality was lowest (about 33%) in first two decades (excluding neonatal group). Mortality in neonatal group was highest (86.38%). Mortality was inversely related to length of incubation period. In cases with incubation period of 7 days or less, mortality was 58.26% in non-neonates and 94.15% in neonates. Mortality was very low (2.14%) in 2,100 cases who did not develop spasms. In cases with spasms mortality was inversely related to the length of period of onset. Temperature of 100 degrees F within first 24 hours of admission was an adverse factor and these cases had higher mortality. Cases were divided into five grades according to the severity. Mortality in each grade was significantly different from that in the other. Mortality was lower in otogenic tetanus while it was higher in post-abortion and post-injection tetanus. Tetanus following penetrating injury carried higher mortality whereas tetanus following abrasions had lower mortality. With head and face as the site of infection, mortality was low while it was high when the site of infection was a trunk. Results were similar with dose of A.T.S. ranging between 5,000 and 60,000 i.u. and tetanus immune globulin, whereas mortality was high with higher and lower dose of A.T.S. or with no A.T.S. Respiratory spasms, respiratory failure, respiratory complications and circulatory failure were the common causes of death.
J C Patel; B C Mehta
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Indian journal of medical sciences     Volume:  53     ISSN:  0019-5359     ISO Abbreviation:  Indian J Med Sci     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-04-04     Completed Date:  2000-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0373023     Medline TA:  Indian J Med Sci     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  393-401     Citation Subset:  IM    
King Edward VII Memorial Hospital, Bombay, India.
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MeSH Terms
Child, Preschool
India / epidemiology
Infant, Newborn
Middle Aged
Retrospective Studies
Survival Rate
Tetanus / epidemiology*

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