Document Detail

Tetanus: a case report.
MedLine Citation:
PMID:  9265826     Owner:  NLM     Status:  MEDLINE    
Tetanus is a rare disease in the United States, with only 40 to 60 cases reported annually. This potentially lethal disease affects unimmunized or partially immunized persons, with the elderly at greatest risk. Tetanus usually follows an injury such as a puncture wound, abrasion, or laceration. The pathogen is an anaerobic, spore-forming, gram-negative, ubiquitous bacillus known as Clostridium tetani. In the vegetative form, it produces a lethal toxin, tetanospasmin, which enters the central nervous system through retrograde axonal transport, resulting in characteristic muscle spasms and tonic contractions. Severe tetanus can cause autonomic instability, respiratory arrest, and cardiac arrest. Patients with tetanus usually require intensive care with dose monitoring and extensive supportive care. Most patients experience full recovery with no signs of neurological sequelae. This case report and discussion illustrate the severity of the disease and the complexity of managing a patient with tetanus.
A C Sudoh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Minnesota medicine     Volume:  80     ISSN:  0026-556X     ISO Abbreviation:  Minn Med     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-10     Completed Date:  1997-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8000173     Medline TA:  Minn Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  43-6     Citation Subset:  IM    
University of Minnesota Medical School's Rural Physician Associate Program (RPAP), Park Rapids, USA.
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MeSH Terms
Combined Modality Therapy
Critical Care / methods
Diagnosis, Differential
Foot Injuries / complications
Tetanus / diagnosis*,  therapy
Wounds, Penetrating / complications

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