Document Detail

Testosterone therapy in Klinefelter's syndrome (a prolonged observation).
MedLine Citation:
PMID:  2619099     Owner:  NLM     Status:  MEDLINE    
Clinical observations and pituitary gonadal hormone data was gathered in six patients with Klinefelter's Syndrome during a prolonged period of time. The secondary sex characteristics increased and the gynecomastia generally disappeared. Personality changes were also noted. In half of the patients, the abnormal level of luteinizing and follicular stimulating hormone remained elevated. An enlarged sella turcica was discovered in one patient. It is concluded that testosterone therapy is beneficial in all patients with Klinefelter's Syndrome.
R H Ruvalcaba
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Andrologia     Volume:  21     ISSN:  0303-4569     ISO Abbreviation:  Andrologia     Publication Date:    1989 Nov-Dec
Date Detail:
Created Date:  1990-02-26     Completed Date:  1990-02-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0423506     Medline TA:  Andrologia     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  535-41     Citation Subset:  IM    
Department of Social and Health Services, Mary Bridge Child, Health Center, Tacoma, WA.
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MeSH Terms
Follow-Up Studies
Gonadotropins / blood*
Gynecomastia / drug therapy*
Klinefelter Syndrome / drug therapy*,  pathology,  physiopathology
Personality / drug effects
Sella Turcica / pathology
Sexual Maturation / drug effects*
Testosterone / blood,  pharmacology,  therapeutic use*
Reg. No./Substance:
0/Gonadotropins; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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