Document Detail


Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores.
MedLine Citation:
PMID:  2400756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation. In comparison with the omnivores, the vegans had 7% higher total T (P = 0.250), 23% higher SHBG (P = 0.001), 3% lower free T (P = 0.580), and 11% higher E2 (P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 d diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids (r 0.37), SHBG and fat (r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol (r-0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.
Authors:
T J Key; L Roe; M Thorogood; J W Moore; G M Clark; D Y Wang
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The British journal of nutrition     Volume:  64     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-10-23     Completed Date:  1990-10-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  111-9     Citation Subset:  IM    
Affiliation:
Cancer Epidemiology Unit, Imperial Cancer Research Fund, Radcliffe Infirmary, Oxford.
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcohol Drinking
Body Mass Index
Diet
Diet, Vegetarian*
Estradiol / blood*
Humans
Male
Prospective Studies
Sex Hormone-Binding Globulin / analysis*
Testosterone / blood*
Chemical
Reg. No./Substance:
0/Sex Hormone-Binding Globulin; 50-28-2/Estradiol; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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