Document Detail


Testosterone replacement therapy and cardiovascular risk factors modification.
MedLine Citation:
PMID:  21539436     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypogonadism in males is associated with increased atherosclerotic disease. Physiologically, testosterone appears to have both positive and negative effects on the cardiovascular system. Testosterone decreases angina and may improve the cardiac healing response after myocardial infarction. Testosterone enhances function in males with heart failure (HF). Testosterone causes water retention and oedema is common in older persons. Oedema should not be used to diagnose HF in older persons. Studies in older persons with HF and frailty have shown a non-statistically lower mortality rate compared to those receiving placebo.
Authors:
Elie J Chahla; Mireille El Hayek; John E Morley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The aging male : the official journal of the International Society for the Study of the Aging Male     Volume:  14     ISSN:  1473-0790     ISO Abbreviation:  Aging Male     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808210     Medline TA:  Aging Male     Country:  England    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  IM    
Affiliation:
GRECC, St. Louis VA Medical Center, St. Louis, MO, USA and Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
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