Document Detail

Testosterone and opioids interact to regulate feeding in a male migratory songbird.
MedLine Citation:
PMID:  1398558     Owner:  NLM     Status:  MEDLINE    
A male migratory songbird (dark-eyed junco, Junco hyemalis) was used as a model for studies on the influence of testosterone (T) on feeding, and on interactive effects on this behavior between T and the opioid antagonist naloxone hydrochloride (Nal). Administered chronically to birds exposed to nonstimulating photoperiods, T increased food intake by 30-58% without altering the body mass, the fat index, or the standard metabolic rate. An intramuscular injection of Nal decreased feeding temporarily in a dose-related manner. T-treated juncos exhibited a decreased sensitivity to the anorexic influence of Nal administration, demonstrating that T interacts with opioids to control food consumption. Neuroendocrine mechanisms that potentially account for this interaction are discussed.
P Deviche
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hormones and behavior     Volume:  26     ISSN:  0018-506X     ISO Abbreviation:  Horm Behav     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-11-04     Completed Date:  1992-11-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217764     Medline TA:  Horm Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  394-405     Citation Subset:  IM    
Institute of Arctic Biology, University of Alaska, Fairbanks 99775.
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MeSH Terms
Birds / physiology*
Endorphins / physiology*
Energy Metabolism / physiology*
Feeding Behavior / physiology*
Sexual Maturation / physiology
Social Environment
Species Specificity
Testosterone / blood*
Reg. No./Substance:
0/Endorphins; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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