Document Detail


Testosterone in the molar vesicle fluid and theca-lutein cyst fluid.
MedLine Citation:
PMID:  629902     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Testosterone was estimated by radioimmunoassay in molar vesicle fluid in 41 patients and theca-lutein cyst fluid in three patients with hydatidiform moles. The testosterone concentration in the molar vesicle fluid ranged from 0.4 ng/ml to 28.1 ng/ml with a mean+/-SEM of 6.0+/-1.0 ng/ml while in the theca-lutein cyst fluid, it ranged from 4.7 ng/ml to 23.5 ng/ml. Oestradiol-17beta and human chorionic gonadotrophin (HCG) were also estimated in the molar vesicle fluid. The oestradiol-17beta concentration ranged from 0.1 ng/ml to 26.2 ng/ml with a mean+/-SEM of 10.7+/-1.1 ng/ml. HCG concentration ranged from 18 000 to 150 000 mIU/ml with a mean+/-SEM of 49 800+/-5 000 mIU/ml. A positive correlation was found between testosterone and oestradiol-17beta (r = +0.37; P less than 0.01) but not between testosterone and HCG (r = 0.32; 0.1 greater than P greater than 0.05). Our findings suggest that molar trophoblast is the major source of testosterone.
Authors:
P C Chew; S S Ratnam; H H Goh
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  85     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-05-24     Completed Date:  1978-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  218-20     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / analysis
Estradiol / analysis
Female
Humans
Hydatidiform Mole / analysis*
Ovarian Cysts / analysis*
Pregnancy
Testosterone / analysis*
Uterine Neoplasms / analysis*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 50-28-2/Estradiol; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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