Document Detail


Testosterone and coronary artery disease in men.
MedLine Citation:
PMID:  20447781     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Coronary artery disease (CAD) is the leading cardiovascular cause of death, and in men, endogenous testosterone concentrations are inversely related to the extent and severity of CAD. Testosterone is known to affect a number of risk factors for CAD and has effects on vascular tone, vasoreactivity and blood flow of blood vessels beyond the reproductive system, indicating that testosterone may be involved in the pathogenesis of CAD. In this review we will present and discuss the actions of endogenous testosterone and testosterone treatment on risk factors for CAD, on the blood vessel wall and blood flow, and on atheroma development and progression, and discuss the potential for testosterone use in men with CAD.
Authors:
Carolyn M Webb; Peter Collins
Publication Detail:
Type:  Journal Article; Review     Date:  2010-05-05
Journal Detail:
Title:  Maturitas     Volume:  67     ISSN:  1873-4111     ISO Abbreviation:  Maturitas     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807333     Medline TA:  Maturitas     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  15-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Cardiovascular Sciences, National Heart & Lung Institute, Imperial College London, London, UK. c.webb@imperial.ac.uk
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