Document Detail


Testosterone concentration within the tunica vaginalis of boys and adult men.
MedLine Citation:
PMID:  7160919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The testosterone level in fluid contained in the tunica vaginalis has been determined in 25 adult men referred for infertility and in 20 boys aged 0-10.5 years operated on for hydrocele. The median concentrations of testosterone were found to be 392 nmole/1 (range 78-957) and 1.1 nmole/1 (range 0.16-182), respectively. The median value for adult men was 20 times the concentration of testosterone found in the peripheral blood of that group while the median value for the boys was 4 times that found in their peripheral blood. It is concluded, firstly, that the high level of testosterone in the peritesticular space of adult men strongly indicates that diffusion of testosterone through the testicular capsule does take place. Secondly, testosterone levels in fluid from the peritesticular space which significantly exceeds those in peripheral blood in prepubertal boys furnishes evidence of testicular secretion of testosterone in that age group. Consequently, the peritesticular tissues such as the epididymis, gubernaculum and scrotum are exposed to quantities of testosterone far exceeding those brought by the general circulation.
Authors:
B Karpe; B Fredricsson; J Svensson; E M Ritzén
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of andrology     Volume:  5     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  549-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Child
Child, Preschool
Genitalia, Male / analysis*,  surgery
Humans
Infant, Newborn
Male
Testicular Hydrocele / surgery
Testosterone / analysis*
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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