| Testis-specific proteins and their role in contraceptive vaccine development. | |
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MedLine Citation:
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PMID: 9560359 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Development of a vaccine(s) based on sperm antigens represents a promising approach for contraception. The utility of an antigen in immunocontraception is contingent upon its testis/sperm specificity and involvement in spermatogenesis and/or fertilization. The aim of the present article is to review the information regarding the proteins that have been reported to be testis/sperm-specific and may have an important function in spermatogenesis and/or fertilization. The potential role of these proteins in the development an antisperm contraceptive vaccine(s) is discussed. |
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Authors:
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R K Naz; C M Vanek |
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Publication Detail:
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Type: Journal Article; Review Date: 1998-04-30 |
Journal Detail:
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Title: Frontiers in bioscience : a journal and virtual library Volume: 3 ISSN: 1093-4715 ISO Abbreviation: Front. Biosci. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 2004-07-09 Completed Date: 2005-05-09 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9709506 Medline TA: Front Biosci Country: United States |
Other Details:
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Languages: eng Pagination: e39-48 Citation Subset: IM |
Affiliation:
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Division of Research, Department of Obstetrics and Gynecology, Medical College of Ohio, Richard D. Ruppert Health Center, 3120 Glendale Avenue, Toledo, OH 43614-5809, USA. rnaz@gemini.mco.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contraception, Immunologic* Humans Male Membrane Proteins / immunology Nuclear Proteins / immunology Protein Biosynthesis Sperm-Ovum Interactions Spermatozoa / enzymology, immunology* Testis / metabolism, physiology Transcription, Genetic Vaccines, Contraceptive* |
| Chemical | |
Reg. No./Substance:
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0/Membrane Proteins; 0/Nuclear Proteins; 0/Vaccines, Contraceptive |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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