Document Detail


Testing the safety of Baxter continuous cardiac output monitoring system.
MedLine Citation:
PMID:  8823649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The safety of a new continuous cardiac output monitoring system, recently introduced by Baxter Healthcare Corporation's Edwards Critical-Care Division, was evaluated in normal sheep. The study compared the biocompatibility and safety of the Vigilance CCO Monitoring System, which employs a continuous cardiac output (CCO) catheter with Baxter Edward's standard Paceport pulmonary artery catheter. The CCO catheter, which monitors hemodynamic pressures and provides continuous measurement of cardiac output based on the thermodilution principle, contains a thermal filament that is powered and controlled by a unique cardiac output monitor. Parameters were measured periodically in conscious animals and complete necropsies were performed after each study. Time Control, Paceport, and four CCO groups were studied. Selected groups were studied for 3 days (acute), 7 days (subacute), and/or 4 weeks after 3 days of continuous use (recovery). Results showed no significant differences between the CCO and Paceport catheters in any of the parameters studied. On gross pathology, observations were similar. The only difference between catheters were microscopic findings of focal subendothelial or subendocardial changes correlated with areas that could have come into contact with the CCO catheter. In acute groups, these changes consisted of a localized myofiber degeneration or necrosis, while in subacute and recovery groups, consisted only of fibrosis. None of the changes were clinically significant. Thus, the CCO catheter, used in conjunction with the Vigilance CCO Monitoring System, appears to pose no additional risk over a standard Paceport catheter in normal sheep after continuous use for up to 7 days.
Authors:
P R Lichtenthal; D Gordan
Related Documents :
16494159 - Perioperative pulse contour cardiac output analysis in a patient with severe cardiac dy...
16038109 - Large pericardial effusions due to systemic lupus erythematosus: a report of eight cases.
6826979 - Cardiac tamponade by loculated pericardial hematoma: limitations of m-mode echocardiogr...
7606999 - Pericardial involvement during the course of myocardial infarction. a long-term clinica...
19436789 - Cardiac tamponade as a sequela to ventriculoatrial shunting for congenital hydrocephalus.
17043419 - The effect of milrinone on the right ventricular function in patients with reduced righ...
9746269 - The diagnostic value of serum homocysteine concentration as a risk factor for coronary ...
25120399 - Right ventricular outflow tract obstruction caused by double-chambered right ventricle ...
16489689 - Left-sided omental torsion with inguinal hernia.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical monitoring     Volume:  12     ISSN:  0748-1977     ISO Abbreviation:  J Clin Monit     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-12-09     Completed Date:  1996-12-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8506707     Medline TA:  J Clin Monit     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  243-9     Citation Subset:  IM    
Affiliation:
Baxter Healthcare Corporation, Round Lake, IL 60073, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biocompatible Materials
Cardiac Output*
Catheterization, Swan-Ganz / adverse effects,  instrumentation
Evaluation Studies as Topic
Female
Heart Catheterization / adverse effects,  instrumentation*
Monitoring, Physiologic / adverse effects,  instrumentation*
Safety
Sheep
Thermodilution
Time Factors
Chemical
Reg. No./Substance:
0/Biocompatible Materials

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Measurement of pulmonary CO2 elimination must exclude inspired CO2 measured at the capnometer sampli...
Next Document:  A multimedia perioperative record keeper for clinical research.