Document Detail


Testing for the random occurrence of sickle cell disease in a study of 100,000 Jamaican newborns.
MedLine Citation:
PMID:  2325194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a screening programme for sickle cell haemoglobinopathies at a maternity hospital in Kingston, Jamaica, 100,000 newborns were screened with the detection of 315 cases of SS disease, and 201 cases of SC disease. There was no upward or downward trend in the frequency of SS or SC births during the screening programme. The sequence numbers of the SS and SC births were analysed to examine whether these cases were randomly distributed among the 100,000 newborns. The occurrence of SS births seems to accord well with the random model but there was an excess of very long intervals between SC births.
Authors:
R J Hayes; G R Serjeant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of tropical medicine and hygiene     Volume:  93     ISSN:  0022-5304     ISO Abbreviation:  J Trop Med Hyg     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-05-18     Completed Date:  1990-05-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0406044     Medline TA:  J Trop Med Hyg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  127-32     Citation Subset:  IM    
Affiliation:
Medical Research Council Laboratories, University of the West Indies, Kingston, Jamaica.
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MeSH Terms
Descriptor/Qualifier:
Anemia, Sickle Cell / epidemiology*
Hemoglobin SC Disease / epidemiology
Humans
Infant, Newborn
Jamaica / epidemiology
Probability
Proportional Hazards Models

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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